CMKLR1 activation ex vivo does not increase proportionally to serum total chemerin in obese humans

Prochemerin is the inactive precursor of the adipokine chemerin. Proteolytic processing is obligatory for the conversion of prochemerin into active chemerin and subsequent regulation of cellular processes via the chemokine-like receptor 1 (CMKLR1). Elevated plasma or serum chemerin concentrations an...

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Bibliographic Details
Published in:Endocr Connect
Main Authors: Toulany, Jay, Parlee, Sebastian D, Sinal, Christopher J, Slayter, Kathryn, McNeil, Shelly, Goralski, Kerry B
Format: Artigo
Language:Inglês
Published: Bioscientifica Ltd 2016
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Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5148798/
https://ncbi.nlm.nih.gov/pubmed/27881447
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1530/EC-16-0065
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