Time-Dependent Loss of Mitochondrial Function Precedes Progressive Histologic Cartilage Degeneration in a Rabbit Meniscal Destabilization Model

The goals of this work were to characterize progression of osteoarthritic cartilage degeneration in a rabbit medial meniscus destabilization (MMD) model and then to use the model to identify pre-histologic disruptions in chondrocyte metabolism under chronically elevated joint contact stresses in viv...

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Bibliografische gegevens
Gepubliceerd in:J Orthop Res
Hoofdauteurs: Goetz, Jessica E., Coleman, Mitchell C., Fredericks, Douglas C., Petersen, Emily, Martin, James A., McKinley, Todd O., Tochigi, Yuki
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2017
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5148713/
https://ncbi.nlm.nih.gov/pubmed/27279147
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jor.23327
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