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Balancing the Interactions of Mg(2+) in Aqueous Solution and with Nucleic Acid Moieties For a Polarizable Force Field Based on the Classical Drude Oscillator Model

Mg(2+) ions are important in biological systems, particularly in stabilizing compact RNA folds. Mg(2+) is strongly polarizing, and representing its interactions in heterogeneous environments is a challenge for empirical force field development. To date, the most commonly used force fields in molecul...

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Detalhes bibliográficos
Publicado no:J Phys Chem B
Main Authors: Lemkul, Justin A., MacKerell, Alexander D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5148688/
https://ncbi.nlm.nih.gov/pubmed/27759379
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jpcb.6b09262
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