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BRAF activates PAX3 to control muscle precursor cell migration during forelimb muscle development

Migration of skeletal muscle precursor cells is a key step during limb muscle development and depends on the activity of PAX3 and MET. Here, we demonstrate that BRAF serves a crucial function in formation of limb skeletal muscles during mouse embryogenesis downstream of MET and acts as a potent indu...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:eLife
Hauptverfasser: Shin, Jaeyoung, Watanabe, Shuichi, Hoelper, Soraya, Krüger, Marcus, Kostin, Sawa, Pöling, Jochen, Kubin, Thomas, Braun, Thomas
Format: Artigo
Sprache:Inglês
Veröffentlicht: eLife Sciences Publications, Ltd 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5148607/
https://ncbi.nlm.nih.gov/pubmed/27906130
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.18351
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