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Efficient immortalization of luminal epithelial cells from human mammary gland by introduction of simian virus 40 large tumor antigen with a recombinant retrovirus.

When defined in terms of markers for normal cell lineages, most invasive breast cancer cells correspond to the phenotype of the common luminal epithelial cell found in the terminal ductal lobular units. Luminal epithelial cells cultured from milk, which have limited proliferative potential, have now...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Principais autores: Bartek, J, Bartkova, J, Kyprianou, N, Lalani, E N, Staskova, Z, Shearer, M, Chang, S, Taylor-Papadimitriou, J
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1991
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC51483/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1708884/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.88.9.3520
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