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Natural Firing Patterns Imply Low Sensitivity of Synaptic Plasticity to Spike Timing Compared with Firing Rate

Synaptic plasticity is sensitive to the rate and the timing of presynaptic and postsynaptic action potentials. In experimental protocols inducing plasticity, the imposed spike trains are typically regular and the relative timing between every presynaptic and postsynaptic spike is fixed. This is at o...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Graupner, Michael, Wallisch, Pascal, Ostojic, Srdjan
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5148241/
https://ncbi.nlm.nih.gov/pubmed/27807166
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0104-16.2016
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