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Natural Firing Patterns Imply Low Sensitivity of Synaptic Plasticity to Spike Timing Compared with Firing Rate

Synaptic plasticity is sensitive to the rate and the timing of presynaptic and postsynaptic action potentials. In experimental protocols inducing plasticity, the imposed spike trains are typically regular and the relative timing between every presynaptic and postsynaptic spike is fixed. This is at o...

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Bibliographic Details
Published in:J Neurosci
Main Authors: Graupner, Michael, Wallisch, Pascal, Ostojic, Srdjan
Format: Artigo
Language:Inglês
Published: Society for Neuroscience 2016
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5148241/
https://ncbi.nlm.nih.gov/pubmed/27807166
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0104-16.2016
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