The Proteome of BLOC-1 Genetic Defects Identifies the Arp2/3 Actin Polymerization Complex to Function Downstream of the Schizophrenia Susceptibility Factor Dysbindin at the Synapse

Proteome modifications downstream of monogenic or polygenic disorders have the potential to uncover novel molecular mechanisms participating in pathogenesis and/or extragenic modification of phenotypic expression. We tested this idea by determining the proteome sensitive to genetic defects in a locu...

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Publicado no:J Neurosci
Main Authors: Gokhale, Avanti, Hartwig, Cortnie, Freeman, Amanda H., Das, Ravi, Zlatic, Stephanie A., Vistein, Rachel, Burch, Amelia, Carrot, Guillemette, Lewis, Arielle F., Nelms, Sheldon, Dickman, Dion K., Puthenveedu, Manojkumar A., Cox, Daniel N., Faundez, Victor
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2016
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5148228/
https://ncbi.nlm.nih.gov/pubmed/27927957
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1321-16.2016
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