Parkin Deficiency Reduces Hippocampal Glutamatergic Neurotransmission by Impairing AMPA Receptor Endocytosis

Mutations in the gene encoding Parkin, an E3 ubiquitin ligase, lead to juvenile-onset Parkinson's disease by inducing the selective death of midbrain dopaminergic neurons. Accumulating evidence indicates that Parkin also has an important role in excitatory glutamatergic neurotransmission, altho...

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Xehetasun bibliografikoak
Argitaratua izan da:J Neurosci
Egile Nagusiak: Cortese, Giuseppe P., Zhu, Mei, Williams, Damian, Heath, Sarah, Waites, Clarissa L.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Society for Neuroscience 2016
Gaiak:
Research Articles
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5148221/
https://ncbi.nlm.nih.gov/pubmed/27903732
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1473-16.2016
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