Application of a low molecular weight antifungal protein from Penicillium chrysogenum (PAF) to treat pulmonary aspergillosis in mice

PAF, a small antifungal protein from Penicillium chrysogenum, inhibits the growth of several pathogenic filamentous fungi, including members of the Aspergillus genus. PAF has been proven to have no toxic effects in vivo in mice by intranasal application. To test its efficacy against invasive pulmona...

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Detalhes bibliográficos
Publicado no:Emerg Microbes Infect
Main Authors: Palicz, Zoltán, Gáll, Tamás, Leiter, Éva, Kollár, Sándor, Kovács, Ilona, Miszti-Blasius, Kornél, Pócsi, István, Csernoch, László, Szentesi, Péter
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5148020/
https://ncbi.nlm.nih.gov/pubmed/27826143
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emi.2016.116
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