GW182-Free microRNA Silencing Complex Controls Post-transcriptional Gene Expression during Caenorhabditis elegans Embryogenesis

MicroRNAs and Argonaute form the microRNA induced silencing complex or miRISC that recruits GW182, causing mRNA degradation and/or translational repression. Despite the clear conservation and molecular significance, it is unknown if miRISC-GW182 interaction is essential for gene silencing during ani...

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Veröffentlicht in:PLoS Genet
Hauptverfasser: Jannot, Guillaume, Michaud, Pascale, Quévillon Huberdeau, Miguel, Morel-Berryman, Louis, Brackbill, James A., Piquet, Sandra, McJunkin, Katherine, Nakanishi, Kotaro, Simard, Martin J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2016
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5147811/
https://ncbi.nlm.nih.gov/pubmed/27935964
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1006484
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