Intron Lariat RNA Inhibits MicroRNA Biogenesis by Sequestering the Dicing Complex in Arabidopsis

Lariat RNAs formed as by-products of splicing are quickly degraded by the RNA debranching enzyme 1 (DBR1), leading to their turnover. Null dbr1 mutants in both animals and plants are embryo lethal, but the mechanism underlying the lethality remains unclear. Here we characterized a weak mutant allele...

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Dettagli Bibliografici
Pubblicato in:PLoS Genet
Autori principali: Li, Ziwei, Wang, Shengpeng, Cheng, Jinping, Su, Chuanbin, Zhong, Songxiao, Liu, Qi, Fang, Yuda, Yu, Yao, Lv, Hong, Zheng, Yun, Zheng, Binglian
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2016
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5147768/
https://ncbi.nlm.nih.gov/pubmed/27870853
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1006422
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