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Photoactivation of an Acid-Sensitive Ion Channel Associated with Vision and Pain

We describe the reversible photoactivation of the acid sensitive ligand-gated ion channel ASIC2a, a mammalian channel found throughout the central and peripheral nervous systems that is associated with vision and pain. We have also shown the activation of GLIC, an acid-sensitive prokaryotic homolog...

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Detalhes bibliográficos
Publicado no:Chembiochem
Main Authors: Shafaat, Oliver S., Winkler, Jay R., Gray, Harry B., Dougherty, Dennis A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5147428/
https://ncbi.nlm.nih.gov/pubmed/27123791
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cbic.201600230
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