Curcumin sensitizes human gastric cancer cells to 5-fluorouracil through inhibition of the NFκB survival-signaling pathway

Fluorouracil (5-FU) is the most commonly used chemotherapeutic agent for gastric cancer (GC). However, the occurrence of resistance to 5-FU treatment poses a major problem for its clinical efficacy. In this study, we found that the NFκB-signaling pathway can mediate 5-FU resistance in GC cells. We d...

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Vydáno v:Onco Targets Ther
Hlavní autoři: Kang, Yanting, Hu, Wanle, Bai, Encheng, Zheng, Hailun, Liu, Zhiguo, Wu, Jianzhang, Jin, Rong, Zhao, Chengguang, Liang, Guang
Médium: Artigo
Jazyk:Inglês
Vydáno: Dove Medical Press 2016
Témata:
Original Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5147405/
https://ncbi.nlm.nih.gov/pubmed/27980427
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S118272
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