T2182C Mutation in 23S rRNA Is Associated with Clarithromycin Resistance in Helicobacter pylori Isolates Obtained in Bangladesh

Twelve clarithromycin-resistant (MIC, ≥1 μg/ml) Helicobacter pylori isolates were analyzed for point mutations in the 23S rRNA gene. Sequence analysis of all of the resistant isolates revealed a T-to-C transition mutation at position 2182. Transformation experiments confirmed that a single T-to-C tr...

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Hlavní autoři: Khan, Rasel, Nahar, Shamsun, Sultana, Jinath, Ahmad, Mian Mashhud, Rahman, Motiur
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2004
Témata:
Mechanisms of Resistance
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC514733/
https://ncbi.nlm.nih.gov/pubmed/15328128
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.48.9.3567-3569.2004
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