T2182C Mutation in 23S rRNA Is Associated with Clarithromycin Resistance in Helicobacter pylori Isolates Obtained in Bangladesh

Twelve clarithromycin-resistant (MIC, ≥1 μg/ml) Helicobacter pylori isolates were analyzed for point mutations in the 23S rRNA gene. Sequence analysis of all of the resistant isolates revealed a T-to-C transition mutation at position 2182. Transformation experiments confirmed that a single T-to-C tr...

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Detalhes bibliográficos

Publicado no:	Antimicrob Agents Chemother
Principais autores:	Khan, Rasel, Nahar, Shamsun, Sultana, Jinath, Ahmad, Mian Mashhud, Rahman, Motiur
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 2004
Assuntos:	Mechanisms of Resistance
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC514733/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15328128/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.48.9.3567-3569.2004
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