Treatment of Experimental Visceral Leishmaniasis with Amphotericin B in Stable Albumin Microspheres

Hydrophilic albumin microspheres are proposed as a new delivery system for amphotericin B (AMB; AMB microspheres). The acute toxicity of AMB microspheres was lower than that of the AMB-deoxycholate (AMB-Doc) reference formulation in hamsters. Lethal doses in healthy and infected animals were improve...

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Detalhes bibliográficos
Main Authors: Sánchez-Brunete, J. A., Dea, M. A., Rama, S., Bolás, F., Alunda, J. M., Raposo, R., Méndez, M. T., Torrado-Santiago, S., Torrado, J. J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2004
Assuntos:
Experimental Therapeutics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC514726/
https://ncbi.nlm.nih.gov/pubmed/15328080
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.48.9.3246-3252.2004
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