Designing Fluoroquinolone Breakpoints for Streptococcus pneumoniae by Using Genetics instead of Pharmacokinetics-Pharmacodynamics

We determined fluoroquinolone microbiological resistance breakpoints for Streptococcus pneumoniae by using genetic instead of pharmacokinetic-pharmacodynamic parameters. The proposed microbiological breakpoints define resistance as the MIC at which >50% of the isolates carry quinolone resistance-...

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Bibliographic Details
Published in:Antimicrob Agents Chemother
Main Authors: Smith, H. J., Noreddin, A. M., Siemens, C. G., Schurek, K. N., Greisman, J., Hoban, C. J., Hoban, D. J., Zhanel, G. G.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 2004
Subjects:
Susceptibility
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC514724/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15328145/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.48.9.3630-3635.2004
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