Reductions in Atherogenic Lipids and Major Cardiovascular Events: A Pooled Analysis of 10 ODYSSEY Trials Comparing Alirocumab With Control

BACKGROUND: A continuous relationship between reductions in low-density lipoprotein cholesterol (LDL-C) and major adverse cardiovascular events (MACE) has been observed in statin and ezetimibe outcomes trials down to achieved levels of 54 mg/dL. However, it is uncertain whether this relationship ext...

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Detalhes bibliográficos
Publicado no:Circulation
Main Authors: Ray, Kausik K., Ginsberg, Henry N., Davidson, Michael H., Pordy, Robert, Bessac, Laurence, Minini, Pascal, Eckel, Robert H., Cannon, Christopher P.
Formato: Artigo
Idioma:Inglês
Publicado em: Lippincott Williams & Wilkins 2016
Assuntos:
Original Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5147039/
https://ncbi.nlm.nih.gov/pubmed/27777279
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCULATIONAHA.116.024604
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