Cadherin-6B proteolysis promotes the neural crest cell epithelial-to-mesenchymal transition through transcriptional regulation

During epithelial-to-mesenchymal transitions (EMTs), cells disassemble cadherin-based junctions to segregate from the epithelia. Chick premigratory cranial neural crest cells reduce Cadherin-6B (Cad6B) levels through several mechanisms, including proteolysis, to permit their EMT and migration. Seria...

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Publicado en:J Cell Biol
Autores principales: Schiffmacher, Andrew T., Xie, Vivien, Taneyhill, Lisa A.
Formato: Artigo
Lenguaje:Inglês
Publicado: The Rockefeller University Press 2016
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Research Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5146998/
https://ncbi.nlm.nih.gov/pubmed/27856599
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201604006
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