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Overexpression of Glucocorticoid-induced Leucine Zipper (GILZ) increases susceptibility to Imiquimod-induced psoriasis and involves cutaneous activation of TGF-β1

Psoriasis vulgaris is a chronic inflammatory skin disease affecting millions of people. Its pathophysiology is complex and involves a skin compartment with epidermal and immune cells which produce cytokines, e.g. belonging to the IL-23–Th17-cell axis. Glucocorticoids (GCs) are the most common therap...

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Bibliografski detalji
Izdano u:Sci Rep
Glavni autori: Carceller, Elena, Ballegeer, Marlies, Deckers, Julie, Riccardi, Carlo, Bruscoli, Stefano, Hochepied, Tino, Libert, Claude, Pérez, Paloma
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2016
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5146970/
https://ncbi.nlm.nih.gov/pubmed/27934944
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep38825
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