High-density Association Mapping and Interaction Analysis of PLA2R1 and HLA Regions with Idiopathic Membranous Nephropathy in Japanese

Although recent studies showed anti-PLA2R antibody plays a crucial role in idiopathic membranous nephropathy (IMN), detailed HLA mapping and interaction between the HLA genes and PLA2R1 have not been investigated in IMN. We genotyped across the PLA2R1 gene and the HLA region, using 183 IMN patients...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Thiri, Myo, Honda, Kenjiro, Kashiwase, Koichi, Mabuchi, Akihiko, Suzuki, Hodaka, Watanabe, Kimio, Nakayama, Masaaki, Watanabe, Tsuyoshi, Doi, Kent, Tokunaga, Katsushi, Noiri, Eisei
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5146917/
https://ncbi.nlm.nih.gov/pubmed/27934873
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep38189
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