Exposure of bovine oocytes and embryos to elevated non-esterified fatty acid concentrations: integration of epigenetic and transcriptomic signatures in resultant blastocysts

BACKGROUND: Metabolic stress associated with negative energy balance in high producing dairy cattle and obesity in women is a risk factor for decreased fertility. Non-esterified fatty acids (NEFA) are involved in this pathogenesis as they jeopardize oocyte and embryo development. Growing evidence in...

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Veröffentlicht in:BMC Genomics
Hauptverfasser: Desmet, K. L. J, Van Hoeck, V., Gagné, D., Fournier, E., Thakur, A., O’Doherty, A. M., Walsh, C. P., Sirard, M. A., Bols, P. E. J., Leroy, J. L. M. R.
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2016
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5146907/
https://ncbi.nlm.nih.gov/pubmed/27931182
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12864-016-3366-y
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