Coagulase negative staphylococcal sepsis in neonates: do we need to adapt vancomycin dose or target?

BACKGROUND: Despite differences in types of infection and causative organisms, pharmacokinetic-pharmacodynamic (PKPD) targets of vancomycin therapy derived from adult studies are suggested for neonates. We aimed to identify doses needed for the attainment of AUC/MIC > 400 and AUC/MIC > 300 in...

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Bibliographic Details
Published in:BMC Pediatr
Main Authors: Padari, Helgi, Oselin, Kersti, Tasa, Tõnis, Metsvaht, Tuuli, Lõivukene, Krista, Lutsar, Irja
Format: Artigo
Language:Inglês
Published: BioMed Central 2016
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5146818/
https://ncbi.nlm.nih.gov/pubmed/27931193
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12887-016-0753-0
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