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Losing your GRP on platelet activation

In this issue of Blood, Kato et al identify compound heterozygous mutations in the Ras guanyl releasing protein 2 (RASGRP2) gene that cause decelerated platelet signaling, reduced platelet aggregation under shear stress, and severe bleeding in an adolescent patient.(1)

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Dades bibliogràfiques
Publicat a:Blood
Autor principal: Holly, Stephen P.
Format: Artigo
Idioma:Inglês
Publicat: American Society of Hematology 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5146748/
https://ncbi.nlm.nih.gov/pubmed/27932328
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2016-10-742742
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