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A study comparing the actions of gabapentin and pregabalin on the electrophysiological properties of cultured DRG neurones from neonatal rats
BACKGROUND: Gabapentin and pregabalin have wide-ranging therapeutic actions, and are structurally related to the inhibitory neurotransmitter GABA. Gabapentin, pregablin and GABA can all modulate voltage-activated Ca(2+ )channels. In this study we have used whole cell patch clamp recording and fura-2...
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| Главные авторы: | , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
BioMed Central
2004
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC514605/ https://ncbi.nlm.nih.gov/pubmed/15294026 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2210-4-14 |
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