Impairment of tubuloglomerular feedback regulation of GFR in ecto-5′-nucleotidase/CD73–deficient mice

Adenosine coordinates organ metabolism and blood supply, and it modulates immune responses. In the kidney it mediates the vascular response elicited by changes in NaCl concentration in the macula densa region of the nephron, thereby serving as an important regulator of GFR. To determine whether aden...

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Main Authors: Castrop, Hayo, Huang, Yuning, Hashimoto, Seiji, Mizel, Diane, Hansen, Pernille, Theilig, Franziska, Bachmann, Sebastian, Deng, Chuxia, Briggs, Josie, Schnermann, Jurgen
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Clinical Investigation 2004
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC514589/
https://ncbi.nlm.nih.gov/pubmed/15343381
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI200421851
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