Hypothalamic PI3K and MAPK differentially mediate regional sympathetic activation to insulin

The action of insulin in the central nervous system produces sympathetic nervous system activation (also called sympathoactivation), although the neuronal intracellular mechanisms that mediate this are unclear. We hypothesized that PI3K and MAPK, the major pathways involved in insulin receptor signa...

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Autors principals: Rahmouni, Kamal, Morgan, Donald A., Morgan, Gina M., Liu, Xuebo, Sigmund, Curt D., Mark, Allyn L., Haynes, William G.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Clinical Investigation 2004
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC514588/
https://ncbi.nlm.nih.gov/pubmed/15343383
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI200421737
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