Low Double-Negative CD3(+)CD4(−)CD8(−) T Cells Are Associated with Incomplete Restoration of CD4(+) T Cells and Higher Immune Activation in HIV-1 Immunological Non-Responders

Failure of immune reconstitution increases the risk of AIDS or non-AIDS related morbidity and mortality in HIV-1-infected patients. CD3(+)CD4(−)CD8(−) T cells, which are usually described as double-negative (DN) T cells, display CD4-like helper and immunoregulatory functions. Here, we have measured...

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Bibliografiske detaljer
Udgivet i:	Front Immunol
Main Authors:	Lu, Xiaofan, Su, Bin, Xia, Huan, Zhang, Xin, Liu, Zhiying, Ji, Yunxia, Yang, Zixuan, Dai, Lili, Mayr, Luzia M., Moog, Christiane, Wu, Hao, Huang, Xiaojie, Zhang, Tong
Format:	Artigo
Sprog:	Inglês
Udgivet:	Frontiers Media S.A. 2016
Fag:	Immunology
Online adgang:	https://ncbi.nlm.nih.gov/pmc/articles/PMC5145861/ https://ncbi.nlm.nih.gov/pubmed/28018346 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2016.00579
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Low Double-Negative CD3(+)CD4(−)CD8(−) T Cells Are Associated with Incomplete Restoration of CD4(+) T Cells and Higher Immune Activation in HIV-1 Immunological Non-Responders

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