PD-L1 Is Not Constitutively Expressed on Tasmanian Devil Facial Tumor Cells but Is Strongly Upregulated in Response to IFN-γ and Can Be Expressed in the Tumor Microenvironment

The devil facial tumor disease (DFTD) is caused by clonal transmissible cancers that have led to a catastrophic decline in the wild Tasmanian devil (Sarcophilus harrisii) population. The first transmissible tumor, now termed devil facial tumor 1 (DFT1), was first discovered in 1996 and has been cont...

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Bibliographic Details
Published in:Front Immunol
Main Authors: Flies, Andrew S., Lyons, A. Bruce, Corcoran, Lynn M., Papenfuss, Anthony T., Murphy, James M., Knowles, Graeme W., Woods, Gregory M., Hayball, John D.
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2016
Subjects:
Immunology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5145852/
https://ncbi.nlm.nih.gov/pubmed/28018348
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2016.00581
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