Enzyme-Mediated Quenching of the Pseudomonas Quinolone Signal (PQS) Promotes Biofilm Formation of Pseudomonas aeruginosa by Increasing Iron Availability

The 2-alkyl-3-hydroxy-4(1H)-quinolone 2,4-dioxygenase HodC was previously described to cleave the Pseudomonas quinolone signal, PQS, which is exclusively used in the complex quorum sensing (QS) system of Pseudomonas aeruginosa, an opportunistic pathogen employing QS to regulate virulence and biofilm...

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Vydáno v:Front Microbiol
Hlavní autoři: Tettmann, Beatrix, Niewerth, Christine, Kirschhöfer, Frank, Neidig, Anke, Dötsch, Andreas, Brenner-Weiss, Gerald, Fetzner, Susanne, Overhage, Joerg
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2016
Témata:
Microbiology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5145850/
https://ncbi.nlm.nih.gov/pubmed/28018312
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2016.01978
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