Increased DC trafficking to lymph nodes and contact hypersensitivity in junctional adhesion molecule-A–deficient mice

Junctional adhesion molecule-A (JAM-A) is a transmembrane adhesive protein expressed at endothelial junctions and in leukocytes. In the present work, we found that DCs also express JAM-A. To evaluate the biological relevance of this observation, Jam-A(–/–) mice were generated and the functional beha...

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Main Authors: Cera, Maria Rosaria, Del Prete, Annalisa, Vecchi, Annunciata, Corada, Monica, Martin-Padura, Ines, Motoike, Toshiyuki, Tonetti, Paolo, Bazzoni, Gianfranco, Vermi, William, Gentili, Francesca, Bernasconi, Sergio, Sato, Thomas N., Mantovani, Alberto, Dejana, Elisabetta
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Clinical Investigation 2004
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC514585/
https://ncbi.nlm.nih.gov/pubmed/15343392
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI200421231
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