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Septins Regulate Developmental Switching from Microdomain to Nanodomain Coupling of Ca(2+) Influx to Neurotransmitter Release at a Central Synapse

Neurotransmitter release depends critically on close spatial coupling of Ca(2+) entry to synaptic vesicles at the nerve terminal; however, the molecular substrates determining their physical proximity are unknown. Using the calyx of Held synapse, where “microdomain” coupling predominates at immature...

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Detalhes bibliográficos
Publicado no:Neuron
Main Authors: Yang, Yi-Mei, Fedchyshyn, Michael J., Grande, Giovanbattista, Aitoubah, Jamila, Tsang, Christopher W., Xie, Hong, Ackerley, Cameron A., Trimble, William S., Wang, Lu-Yang
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5145303/
https://ncbi.nlm.nih.gov/pubmed/20624595
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2010.06.003
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