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Apparent Hypothalamic-Pituitary-Adrenal Axis Suppression via Reduction of Interleukin-6 by Glucocorticoid Therapy in Systemic Autoimmune Diseases

CONTEXT: Suppression of the hypothalamic-pituitary-adrenal (HPA) axis is a serious complication of systemic glucocorticoid therapy. OBJECTIVE: To clarify the influence of proinflammatory cytokines on the HPA axis after onset of glucocorticoid therapy in patients with systemic autoimmune diseases. PA...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Fujio, Natsuki, Masuoka, Shotaro, Shikano, Kotaro, Kusunoki, Natsuko, Nanki, Toshihiro, Kawai, Shinichi
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5145206/
https://ncbi.nlm.nih.gov/pubmed/27930715
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0167854
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