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Inactivation of Individual SeqA Binding Sites of the E. coli Origin Reveals Robustness of Replication Initiation Synchrony

The Escherichia coli origin of replication, oriC, comprises mostly binding sites of two proteins: DnaA, a positive regulator, and SeqA, a negative regulator. SeqA, although not essential, is required for timely initiation, and during rapid growth, synchronous initiation from multiple origins. Unlike...

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Vydáno v:PLoS One
Hlavní autoři: Jha, Jyoti K., Chattoraj, Dhruba K.
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2016
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5145175/
https://ncbi.nlm.nih.gov/pubmed/27930658
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0166722
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