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A Novel Frizzled-Based Screening Tool Identifies Genetic Modifiers of Planar Cell Polarity in Drosophila Wings

Most mutant alleles in the Fz-PCP pathway genes were discovered in classic Drosophila screens looking for recessive loss-of-function (LOF) mutations. Nonetheless, although Fz-PCP signaling is sensitive to increased doses of PCP gene products, not many screens have been performed in the wing under ge...

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Dettagli Bibliografici
Pubblicato in:G3 (Bethesda)
Autori principali: Carvajal-Gonzalez, Jose Maria, Mulero-Navarro, Sonia, Smith, Michael, Mlodzik, Marek
Natura: Artigo
Lingua:Inglês
Pubblicazione: Genetics Society of America 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5144966/
https://ncbi.nlm.nih.gov/pubmed/27729438
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/g3.116.035535
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