X Chromosome Crossover Formation and Genome Stability in Caenorhabditis elegans Are Independently Regulated by xnd-1

The germ line efficiently combats numerous genotoxic insults to ensure the high fidelity propagation of unaltered genomic information across generations. Yet, germ cells in most metazoans also intentionally create double-strand breaks (DSBs) to promote DNA exchange between parental chromosomes, a pr...

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Bibliographic Details
Published in:G3 (Bethesda)
Main Authors: McClendon, T. Brooke, Mainpal, Rana, Amrit, Francis R. G., Krause, Michael W., Ghazi, Arjumand, Yanowitz, Judith L.
Format: Artigo
Language:Inglês
Published: Genetics Society of America 2016
Subjects:
Investigations
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5144962/
https://ncbi.nlm.nih.gov/pubmed/27678523
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/g3.116.035725
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