Oral Monomethyl Fumarate Therapy Ameliorates Retinopathy in a Humanized Mouse Model of Sickle Cell Disease

Aims: Sickle retinopathy (SR) is a major cause of blindness in sickle cell disease (SCD). The genetic mutation responsible for SCD is known, however; oxidative stress and inflammation also figure prominently in the development and progression of pathology. Development of therapies for SR is hampered...

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Bibliographic Details
Published in:Antioxid Redox Signal
Main Authors: Promsote, Wanwisa, Powell, Folami Lamoke, Veean, Satyam, Thounaojam, Menaka, Markand, Shanu, Saul, Alan, Gutsaeva, Diana, Bartoli, Manuela, Smith, Sylvia B., Ganapathy, Vadivel, Martin, Pamela M.
Format: Artigo
Language:Inglês
Published: Mary Ann Liebert, Inc. 2016
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Original Research Communications
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5144884/
https://ncbi.nlm.nih.gov/pubmed/27393735
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/ars.2016.6638
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