Aspartate-β-hydroxylase (ASPH): A potential therapeutic target in human malignant gliomas

BACKGROUND: Despite therapeutic advances, survival with glioblastoma multiforme (GBM) remains below 15 months from diagnosis due to GBM’s highly infiltrative nature which precludes complete surgical resection. Patient outcomes could potentially be improved by targeting genes and pathways that drive...

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Detalhes bibliográficos
Publicado no:Heliyon
Main Authors: Sturla, Lisa-Marie, Tong, Ming, Hebda, Nick, Gao, Jinsong, Thomas, John-Michael, Olsen, Mark, de la Monte, Suzanne M.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5144823/
https://ncbi.nlm.nih.gov/pubmed/27981247
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.heliyon.2016.e00203
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