Partitioning heritability analysis reveals a shared genetic basis of brain anatomy and schizophrenia

Schizophrenia is a devastating neurodevelopmental disorder with a complex genetic etiology. Widespread cortical gray matter loss has been observed in patients and prodromal samples. However, it remains unresolved whether schizophrenia-associated cortical structure variations arise due to disease eti...

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Publié dans:Mol Psychiatry
Auteurs principaux: Lee, Phil H., Baker, Justin T., Holmes, Avram J., Jahanshad, Neda, Ge, Tian, Jung, Jae-Yoon, Cruz, Yanela, Manoach, Dara S., Hibar, Derrek P., Faskowitz, Joshua, McMahon, Katie L., de Zubicaray, Greig I., Martin, Nicolas H., Wright, Margaret J., Öngür, Dost, Buckner, Randy, Roffman, Joshua, Thompson, Paul M., Smoller, Jordan W.
Format: Artigo
Langue:Inglês
Publié: 2016
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5144575/
https://ncbi.nlm.nih.gov/pubmed/27725656
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mp.2016.164
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