Development of mannose-anchored thiolated amphotericin B nanocarriers for treatment of visceral leishmaniasis

AIM: Our goal was to improve treatment outcomes for visceral leishmaniasis by designing nanocarriers that improve drug biodistribution and half-life. Thus, long-acting mannose-anchored thiolated chitosan amphotericin B nanocarrier complexes (MTC AmB) were developed and characterized. MATERIALS &...

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Veröffentlicht in:Nanomedicine (Lond)
Hauptverfasser: Shahnaz, Gul, Edagwa, Benson J, McMillan, JoEllyn, Akhtar, Sohail, Raza, Abida, Qureshi, Naveeda A, Yasinzai, Masoom, Gendelman, Howard E
Format: Artigo
Sprache:Inglês
Veröffentlicht: Future Medicine Ltd 2017
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5144491/
https://ncbi.nlm.nih.gov/pubmed/27879160
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2217/nnm-2016-0325
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