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Translation arrest of SecM is essential for the basal and regulated expression of SecA

The SecM protein of Escherichia coli contains an arrest sequence (F(150)XXXXWIXXXXGIRAGP(166)), which interacts with the ribosomal exit tunnel to halt translation elongation beyond Pro-166. This inhibition is reversed by active export of the nascent SecM chain. Here, we studied the physiological rol...

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Autori principali: Murakami, Akiko, Nakatogawa, Hitoshi, Ito, Koreaki
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2004
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC514405/
https://ncbi.nlm.nih.gov/pubmed/15302932
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0404907101
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