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Translation arrest of SecM is essential for the basal and regulated expression of SecA

The SecM protein of Escherichia coli contains an arrest sequence (F(150)XXXXWIXXXXGIRAGP(166)), which interacts with the ribosomal exit tunnel to halt translation elongation beyond Pro-166. This inhibition is reversed by active export of the nascent SecM chain. Here, we studied the physiological rol...

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Bibliografiske detaljer
Main Authors: Murakami, Akiko, Nakatogawa, Hitoshi, Ito, Koreaki
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2004
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC514405/
https://ncbi.nlm.nih.gov/pubmed/15302932
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0404907101
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