Preparation, properties, and plasma retention of human hemoglobin derivatives: comparison of uncrosslinked carboxymethylated hemoglobin with crosslinked tetrameric hemoglobin.

Human hemoglobin A has been crosslinked by diisothiocyanatobenzenesulfonate to give a limited number of products in a yield of approximately 70%. The predominant product was crosslinked between subunits within a tetramer and had a Mr of 64,000; no higher Mr species were formed. This product had one...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Manning, L R, Morgan, S, Beavis, R C, Chait, B T, Manning, J M, Hess, J R, Cross, M, Currell, D L, Marini, M A, Winslow, R M
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1991
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC51440/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2014253/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.88.8.3329
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