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A minimum structure of aminoglycosides that causes an initiation shift of trans-translation

Trans-translation is an unusual translation in which transfer-messenger RNA plays a dual function—as a tRNA and an mRNA—to relieve the stalled translation on the ribosome. It has been shown that paromomycin, a typical member of a 4,5-disubstituted class of aminoglycosides, causes a shift of the tran...

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Detalhes bibliográficos
Main Authors: Konno, Takayuki, Takahashi, Toshiharu, Kurita, Daisuke, Muto, Akira, Himeno, Hyouta
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC514373/
https://ncbi.nlm.nih.gov/pubmed/15295039
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkh750
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