MAGE-A1 interacts with adaptor SKIP and the deacetylase HDAC1 to repress transcription

MAGE-A1 belongs to a family of 12 genes that are active in various types of tumors and silent in normal tissues except in male germ-line cells. The MAGE-encoded antigens recognized by T cells are highly tumor-specific targets for T cell-oriented cancer immunotherapy. The function of MAGE-A1 is curre...

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Main Authors: Laduron, Sandra, Deplus, Rachel, Zhou, Sifang, Kholmanskikh, Olga, Godelaine, Danièle, De Smet, Charles, Hayward, S. Diane, Fuks, François, Boon, Thierry, De Plaen, Etienne
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2004
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC514365/
https://ncbi.nlm.nih.gov/pubmed/15316101
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkh735
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