Tribbles ortholog NIPI-3 and bZIP transcription factor CEBP-1 regulate a Caenorhabditis elegans intestinal immune surveillance pathway

BACKGROUND: Many pathogens secrete toxins that target key host processes resulting in the activation of immune pathways. The secreted Pseudomonas aeruginosa toxin Exotoxin A (ToxA) disrupts intestinal protein synthesis, which triggers the induction of a subset of P. aeruginosa-response genes in the...

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Detalhes bibliográficos
Publicado no:BMC Biol
Main Authors: McEwan, Deborah L., Feinbaum, Rhonda L., Stroustrup, Nicholas, Haas, Wilhelm, Conery, Annie L., Anselmo, Anthony, Sadreyev, Ruslan, Ausubel, Frederick M.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5143455/
https://ncbi.nlm.nih.gov/pubmed/27927200
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12915-016-0334-6
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