The role of local IL6/JAK2/STAT3 signaling in high glucose–induced podocyte hypertrophy

BACKGROUND: Interleukin-6 (IL6) is an important regulator of cellular hypertrophy through the gp130/Janus kinase 2 (JAK2)/signal transducer and activator of transcription 3 (STAT3) pathway. We tested the hypothesis that IL6 and its downstream gp130/JAK2/STAT3 pathway participated in high glucose (HG...

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Bibliographic Details
Published in:Kidney Res Clin Pract
Main Authors: Jo, Hyung Ah, Kim, Joo-Young, Yang, Seung Hee, Han, Seung Seok, Joo, Kwon Wook, Kim, Yon Su, Kim, Dong Ki
Format: Artigo
Language:Inglês
Published: Elsevier 2016
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Original Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5143438/
https://ncbi.nlm.nih.gov/pubmed/27957415
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.krcp.2016.09.003
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