Expression of μ-protocadherin is negatively regulated by the activation of the β-catenin signaling pathway in normal and cancer colorectal enterocytes

Mu-protocadherin (MUCDHL) is an adhesion molecule predominantly expressed by colorectal epithelial cells which is markedly downregulated upon malignant transformation. Notably, treatment of colorectal cancer (CRC) cells with mesalazine lead to increased expression of MUCDHL, and is associated with s...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Montorsi, L, Parenti, S, Losi, L, Ferrarini, F, Gemelli, C, Rossi, A, Manco, G, Ferrari, S, Calabretta, B, Tagliafico, E, Zanocco-Marani, T, Grande, A
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5143391/
https://ncbi.nlm.nih.gov/pubmed/27310872
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2016.163
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