High Expression of PHGDH Predicts Poor Prognosis in Non–Small Cell Lung Cancer()

Tumors have exceptionally high demands for energy and anabolism because of their rapid growth. The de novo serine synthesis pathway initiated by phosphoglycerate dehydrogenase (PHGDH) has been recognized as a hallmark of metabolic adaption in carcinogenesis. The oncogenic role and prognostic value o...

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Publicado en:Transl Oncol
Autores principales: Zhu, Jinhong, Ma, Jianqun, Wang, Xudong, Ma, Tianjiao, Zhang, Shu, Wang, Wei, Zhou, Xiaoyu, Shi, Jiahai
Formato: Artigo
Lenguaje:Inglês
Publicado: Neoplasia Press 2016
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Original article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5143353/
https://ncbi.nlm.nih.gov/pubmed/27916294
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tranon.2016.08.003
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