Structure of the NPr:EIN(Ntr) Complex: Mechanism for Specificity in Paralogous Phosphotransferase Systems

Paralogous enzymes arise from gene duplication events that confer a novel function, although it is unclear how cross-reaction between the original and duplicate protein interaction network is minimized. We investigated HPr:EI(sugar) and NPr:EI(Ntr), the initial complexes of paralogous phosphorylatio...

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Bibliographic Details
Published in:Structure
Main Authors: Strickland, Madeleine, Stanley, Ann Marie, Wang, Guangshun, Botos, Istvan, Schwieters, Charles D., Buchanan, Susan K., Peterkofsky, Alan, Tjandra, Nico
Format: Artigo
Language:Inglês
Published: 2016
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5143221/
https://ncbi.nlm.nih.gov/pubmed/27839951
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2016.10.007
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