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Metastatic basal cell carcinoma with amplification of PD-L1: exceptional response to anti-PD1 therapy
Metastatic basal cell carcinomas are rare malignancies harbouring Hedgehog pathway alterations targetable by SMO antagonists (vismodegib/sonidegib). We describe, for the first time, the molecular genetics and response of a patient with Hedgehog inhibitor-resistant metastatic basal cell carcinoma who...
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| Izdano u: | NPJ Genom Med |
|---|---|
| Glavni autori: | , , , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Nature Publishing Group
2016
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5142752/ https://ncbi.nlm.nih.gov/pubmed/27942391 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npjgenmed.2016.37 |
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