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Functional characterisation of long intergenic non-coding RNAs through genetic interaction profiling in Saccharomyces cerevisiae

BACKGROUND: Transcriptome studies have revealed that many eukaryotic genomes are pervasively transcribed producing numerous long non-coding RNAs (lncRNAs). However, only a few lncRNAs have been ascribed a cellular role thus far, with most regulating the expression of adjacent genes. Even less lncRNA...

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Publicado en:BMC Biol
Main Authors: Kyriakou, Dimitris, Stavrou, Emmanouil, Demosthenous, Panayiota, Angelidou, Georgia, San Luis, Bryan-Joseph, Boone, Charles, Promponas, Vasilis J., Kirmizis, Antonis
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2016
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5142380/
https://ncbi.nlm.nih.gov/pubmed/27927215
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12915-016-0325-7
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